Mood

Why Our Omega-3s Are Powerful Mood Supplements

If you’re looking to keep your mood steady using supplements and a good diet, you’ve come to the right place. Nearly 4 decades of research reveal Omega-3s nourish a healthy spirit.*

Epidemiological studies show people who eat a lot of Omega-3-rich fish tend to be happier people. In clinical studies, people struggling with mood feel pretty good after supplementing regularly with fish oil Omega-3s.1* In fact, the evidence is so strong, the U.S. army has been considering adding Omega-3s to standard rations as a way to help soldiers deal with the mentally grueling conditions and after-effects of military service.2*

Much of the research doesn’t distinguish between DHA and EPA. It just identifies Omega-3s in general for their mood buoying benefits. However, lately more research suggests EPA might be more effective in supporting good mental health.*

Wouldn’t you love to get up each morning mentally charged up to take on the day? OmegaVia EPA 500 gives you concentrated EPA for optimum mood support.* Our Ultra-Concentrated Omega-3 gives you a big supply of unopposed EPA that will help you feel upbeat, along with some DHA as well.*

After reading all the testimonials and studying the facts about your product I ordered 3 bottles and started her on one pill a day with breakfast. Within two weeks I noticed she was no longer complaining and her mood had improved considerably. I then increased her dosage to 2 pills a day one with breakfast and one with dinner and within four weeks – the results were nothing short of a miracle….and her mood is one of peace and tranquility unlike anything I have ever seen in the 35 yrs we have been married.*

Jack and Janice Bagley Granby, CT

Check out our great Omega-3 mood supplements

Mood Supplements FAQ

Why is high-EPA fish oil often recommended for mood balance?

Omega-3 fatty acids are often recommended to support mood regulation and alleviate symptoms of mood disorders, like depression. An Omega-3 deficiency is associated with developing mental health concerns, such as depression, ADHD, and bipolar disorder [1]. EPA and DHA are particularly linked to mental health and mood balance support. Research has found that higher doses of EPA may improve depressive symptoms [2].

If you aren’t getting enough Omega-3s through your diet, taking a high-EPA fish oil can help you get those nutrients in to support mood health.

How does Omega-3 interact with brain chemicals related to mood?

Omega-3s are known for their anti-inflammatory properties, and these properties may play a role in improving mood.

DHA is a key component of the brain that influences the release of neurotransmitters, the chemical messengers that carry signals between nerve cells [3]. Supplementing Omega-3s in the body can lead to better neural and synaptic plasticity, allowing dopamine and serotonin—two essential neurotransmitters that affect mood [4]—to travel more effectively.

What dosage of EPA is typically used in clinical mood studies?

Research is ongoing to determine the ideal dose of EPA for mood benefits. For adults, the adequate daily intake of Omega-3s is between 1.1 g for females and 1.6g for males based on combined EPA and DHA Omega-3 supplements5. Current research involves doses of EPA greater than 1g, but it is not yet conclusive whether this is the optimal daily amount to support mood health.

OmegaVia’s EPA 500 supplement softgels contain 500 mg of EPA. Per the supplement facts, the serving size is one 500 mg softgel.

Can Omega-3 help with emotional wellness during stressful periods?

Increasing your consumption of Omega-3s or supplementing DHA and EPA may offer mood benefits [1]. Start by trying to incorporate more Omega-3 into your diet with foods like salmon, sardines, or mussels. OmegaVia can help you supplement your intake for emotional wellness.

Pairing the increase of Omega-3s with lifestyle changes, like gentle yoga exercise, breathing meditation, and body scanning techniques, can also help you manage stress.

Sources

  1. Lange, K. W. (16 July 2019). Omega-3 fatty acids and mental health. Global Health Journal. Retrieved February 3, 2026, from https://www.sciencedirect.com/science/article/pii/S241464472030004X
  2. Dyall, S. C., Malau, I. A., Su, K. (1 March 2025). Omega-3 polyunsaturated fatty acids in depression: insights from recent clinical trials. Current Opinion in Clinical Nutrition and Metabolic Care. Retrieved February 3, 2026, from https://pubmed.ncbi.nlm.nih.gov/39912390/
  3. Mehdi, S. et. al. (27 January 2023). Omega-3 Fatty Acids Supplementation in the Treatment of Depression: An Observational Study. Journal of Personalized Medicine. Retrieved February 3, 2026, from https://pmc.ncbi.nlm.nih.gov/articles/PMC9962071/
  4. Sheffler, Z., Reddy, V., Pillarisetty, L. S. (1 May 2023). Physiology, Neurotransmitters. StatPearls. Retrieved February 3, 2026, from https://www.ncbi.nlm.nih.gov/books/NBK539894/
  5. Omega-3 Fatty Acids. National Institutes of Health: Office of Dietary Supplements. Retrieved February 3, 2026, from https://ods.od.nih.gov/factsheets/Omega3FattyAcids-HealthProfessional/